Journal article

Vaccination of bovines against Echinococcus granulosus (cystic echinococcosis)

DD Heath, C Robinson, T Shakes, Y Huang, T Gulnur, B Shi, Z Zhang, GA Anderson, MW Lightowlers

Vaccine | Published : 2012

Abstract

Hydatid disease is an important human zoonosis. Humans become infected from carnivores that are infected with the . Echinococcus granulosus tapeworm. Carnivores become infected after consuming hydatid cysts from grazing animals, which are generally sheep, goats and cattle. A vaccine, known as EG95, can protect sheep and goats against cystic echinococcosis. This paper describes the adaptation of the EG95 vaccine for use in cattle. The monitoring of results used serology and also infection with . E. granulosus eggs, followed by necropsy. Immunisation with living . E. granulosus oncospheres showed that cattle could be immunised against . E. granulosus. Immunisation of cattle with EG95 plus Quil..

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University of Melbourne Researchers