Journal article
Vaccination of bovines against Echinococcus granulosus (cystic echinococcosis)
DD Heath, C Robinson, T Shakes, Y Huang, T Gulnur, B Shi, Z Zhang, GA Anderson, MW Lightowlers
Vaccine | Published : 2012
Abstract
Hydatid disease is an important human zoonosis. Humans become infected from carnivores that are infected with the . Echinococcus granulosus tapeworm. Carnivores become infected after consuming hydatid cysts from grazing animals, which are generally sheep, goats and cattle. A vaccine, known as EG95, can protect sheep and goats against cystic echinococcosis. This paper describes the adaptation of the EG95 vaccine for use in cattle. The monitoring of results used serology and also infection with . E. granulosus eggs, followed by necropsy. Immunisation with living . E. granulosus oncospheres showed that cattle could be immunised against . E. granulosus. Immunisation of cattle with EG95 plus Quil..
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Grants
Awarded by Foundation for Research, Science and Technology
Funding Acknowledgements
[ "The major amount of this work was funded by the New Zealand Foundation for Research, Science and Technology (FRST).", "Funding from the Australian National Health and Medical Research Council (grant numbers 350279, 628320, 100354) (ML) is acknowledged." ]